Find Research Outputs

2019
3 Downloads (Pure)

A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila

Hannaford, M., Loyer, N., Tonelli, F., Zoltner, M. & Januschke, J., 29 Jan 2019, In : Development. 146, 2, p. 1-11 11 p., dev170589.

Research output: Contribution to journalArticle

Open Access
File
Drosophila
Phosphotransferases
Drosophila Proteins
Cell Polarity
Nuclear Envelope
4 Downloads (Pure)

A cognitive forcing tool to mitigate cognitive bias: A randomised control trial

O'Sullivan, E. D. & Schofield, S. J., 8 Jan 2019, In : BMC Medical Education. 19, 1, p. 1-8 8 p., 12.

Research output: Contribution to journalArticle

Open Access
File
trend
diagnostic
Ireland
medical student
republic
1 Downloads (Pure)

A comparative map of macroautophagy and mitophagy in the vertebrate eye

McWilliams, T. G., Prescott, A., Villarejo-Zori, B., Ball, G., Boya, P. & Ganley, I., 20 Feb 2019, In : Autophagy. 13 p.

Research output: Contribution to journalArticle

Open Access
File
Mitochondrial Degradation
Autophagy
Vertebrates
Retina
Homeostasis

A comparison of haemostatic biomarkers during low-risk patients undergoing cardiopulmonary bypass using either conventional centrifugal cell salvage or the HemoSep device

Boyle, G., Kuffel, A., Parmar, K., Gibson, K., Smith, M., Grehan, A., Hunt, B. J. & Chambers, D. J., 1 Jan 2019, In : Perfusion. 34, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

Hemostatics
Cardiopulmonary Bypass
Biomarkers
Equipment and Supplies
Partial Thromboplastin Time
fragments
synthesis
Hydrogenation
Quality control
Hydrogen
4 Downloads (Pure)

A critical comparison of technologies for a plant genome sequencing project

Paajanen, P., Kettleborough, G., Lopez-Girona, E., Giolai, M., Heavens, D., Baker, D., Lister, A., Wilde, G., Hein, I., Macaulay, I., Bryan, G. J. & Clark, M. D., 9 Jan 2019, In : Giga Science.

Research output: Contribution to journalArticle

Open Access
File
genome assembly
genome
genomics
plant biology
DNA
10 Downloads (Pure)

Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study

Kerr, D. M. I., Brooksbank, K. J. M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M. & Delles, C., Jan 2019, In : Journal of Hypertension. 37, 1, p. 154-166 13 p.

Research output: Contribution to journalArticle

Open Access
File
Cross-Over Studies
Tobacco
Blood Vessels
Healthy Volunteers
Smoking

Adoption of innovation in agriculture: A critical review of economic and psychological models

Borges, J. A. R., Oude Lansink, A. G. J. M. & Emvalomatis, G., 1 Jan 2019, In : International Journal of Innovation and Sustainable Development. 13, 1, p. 36-56 21 p.

Research output: Contribution to journalArticle

Agriculture
Innovation
Economics
Theory of planned behavior
Psychological

Advancing the science of literature reviewing in social research: the focused mapping review and synthesis

Bradbury-Jones, C., Breckenridge, J., Clark, M. T., Herber, O. R., Jones, C. & Taylor, J., 18 Feb 2019, In : International Journal of Social Research Methodology.

Research output: Contribution to journalArticle

social research
science
evidence
knowledge production
geography

A dynamic reference change value model applied to ongoing assessment of the steady state of a biomarker using more than two serial results

Lund, F., Hyltoft Petersen, P. & Fraser, C. G., 25 Feb 2019, In : Annals of Clinical Biochemistry.

Research output: Contribution to journalArticle

Biomarkers
Reference Values

A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for Use in Double Electron Electron Resonance Distance Measurements

Shah, A., Roux, A., Starck, M., Mosely, J. A., Stevens, M., Norman, D. G., Hunter, R. I., El Mkami, H., Smith, G. M., Parker, D. & Lovett, J. E., 18 Feb 2019, In : Inorganic Chemistry. 11 p.

Research output: Contribution to journalArticle

Electron resonance
Spin Labels
Distance measurement
Gadolinium
gadolinium
3 Downloads (Pure)

A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia

Huang, Y., Kee, C-S., Hocking, P. M., Williams, C., Yip, S. P. & Guggenheim, J. A., 1 Feb 2019, In : Investigative Ophthalmology & Visual Science. 60, 2, p. 559-569 11 p.

Research output: Contribution to journalArticle

Open Access
File
Genome-Wide Association Study
Myopia
Gene-Environment Interaction
Refractive Errors
Genetic Predisposition to Disease

Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients

Lanz, J., Bouwes Bavinck, J. N., Westhuis, M., Quint, K. D., Harwood, C. A., Nasir, S., Van-de-Velde, V., Proby, C. M., Ferrándiz, C., Genders, R. E., Del Marmol, V., Forchetti, G., Hafner, J., Vital, D. G. & Vital, D. G., Jan 2019, In : JAMA Dermatology. 155, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Transplants
Neoplasms
Neoplasm Metastasis
Organ Transplantation
3 Downloads (Pure)

A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

Plummer, S., Wallace, S., Ball, G., Lloyd, R., Schiapparelli, P., Quiñones-Hinojosa, A., Hartung, T. & Pamies, D., 5 Feb 2019, In : Scientific Reports. 9, 1, p. 1-11 11 p., 1407.

Research output: Contribution to journalArticle

Open Access
File
temozolomide
Precision Medicine
Glioblastoma
Brain Neoplasms
Doxorubicin
4 Citations (Scopus)
10 Downloads (Pure)

Albugo candida race diversity, ploidy and host-associated microbes revealed using DNA sequence capture on diseased plants in the field

Jouet, A., Saunders, D. G. O., McMullan, M., Ward, B., Furzer, O., Jupe, F., Cevik, V., Hein, I., Thilliez, G. J. A., Holub, E., Oosterhout, C. V. & Jones, J. D. G., Feb 2019, In : New Phytologist. 221, 3, p. 1529-1543 15 p.

Research output: Contribution to journalArticle

Open Access
File
Albugo candida
Plant Diseases
Ploidies
ploidy
Candida
2 Downloads (Pure)

A localized surface plasmon resonance-amplified immunofluorescence biosensor for ultrasensitive and rapid detection of nonstructural protein 1 of Zika virus

Takemura, K., Adegoke, O., Suzuki, T. & Park, E. Y., 31 Jan 2019, In : PLoS ONE. 14, 1, p. 1-14 14 p., e0211517.

Research output: Contribution to journalArticle

Open Access
File
Zika virus
surface plasmon resonance
Surface Plasmon Resonance
biosensors
Surface plasmon resonance

A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In : Scientific Reports. p. 1-10 10 p., 3591.

Research output: Contribution to journalArticle

Open Access
File
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism
Biomarkers
Blood Pressure
HDL Lipoproteins
Methylenetetrahydrofolate Dehydrogenase (NADP)
dehydrogenases
inhibitors
Ligands
enzymes

A new approach for determination of free carriers lifetime and density of localised states in disordered semiconductors

Belgacem, H. & Reynolds, S., 2019, In : Philosophical Magazine. 99, 2, p. 131-147 17 p.

Research output: Contribution to journalArticle

Carrier lifetime
Photoconductivity
Carrier concentration
Semiconductor materials
Laplace transforms

An Expanded Mixed Finite Element Method for Two-dimensional Sobolev Equations

Li, N., Lin, P. & Gao, F., 1 Mar 2019, In : Journal of Computational and Applied Mathematics. 348, p. 342-355 14 p.

Research output: Contribution to journalArticle

Mixed Finite Element Method
Finite element method
Optimal Error Estimates
Verify
Numerical Examples

An Image Processing System for Char Combustion Reactivity Characterisation

Chaves, D., Trucco, E., Barraza, J. & Trujillo, M. P., Apr 2019, In : Computers in Industry. 106, p. 60-70 11 p.

Research output: Contribution to journalArticle

Image processing
Coal
Petrology
Coal combustion
Fuel burners

Anti-microbial Resistance In Atopic Dermatitis: Need for an Urgent Rethink

Harkins, C. P., Holden, M. T. G. & Irvine, A. D., Mar 2019, In : Annals of Allergy, Asthma & Immunology. 122, 3, p. 236-240 5 p.

Research output: Contribution to journalComment/debate

4 Downloads (Pure)

A numerical model based on ALE formulation to predict crack propagation in sandwich structures

Funari, M. F., Greco, F., Lonetti, P. & Spadea, S., Jan 2019, In : Frattura ed Integrita Strutturale. 13, 47, p. 277-293 17 p.

Research output: Contribution to journalArticle

Open Access
File
Sandwich structures
Numerical models
Crack propagation
Debonding
Skin
1 Downloads (Pure)

A patient-centred intervention to improve the management of multimorbidity in general practice: the 3D RCT

Salisbury, C., Man, M-S., Chaplin, K., Mann, C., Bower, P., Brookes, S., Duncan, P., Fitzpatrick, B., Gardner, C., Gaunt, D. M., Guthrie, B., Hollinghurst, S., Kadir, B., Lee, V., McLeod, J., Mercer, S. W., Moffat, K. R., Moody, E., Rafi, I., Robinson, R. & 2 othersShaw, A. & Thorn, J., Feb 2019, In : Health Services and Delivery Research. 7, 5, 276 p.

Research output: Contribution to journalArticle

Open Access
File
General Practice
Comorbidity
Patient-Centered Care
Quality of Life
Cost of Illness
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care
3 Downloads (Pure)

Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

Reed, L., Indra, R., Mrizova, I., Moserova, M., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M., 1 Mar 2019, In : Toxicology and Applied Pharmacology. 366, p. 64-74 11 p.

Research output: Contribution to journalArticle

Open Access
File
ellipticine
Cytochromes b5
NADPH-Ferrihemoprotein Reductase
Cytochrome P-450 Enzyme System
Oxidoreductases

A Practical Guide to Barley Crossing

Thomas, W. T. B., Bull, H., Booth, A., Hamilton, R., Forster, B. P. & Franckowiak, J. D., 1 Jan 2019, Barley: Methods in Molecular Biology. Harwood, W. A. (ed.). New York: Humana Press, Vol. 1900. p. 21-36 16 p. (Methods in Molecular Biology (Clifton, N.J.)).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Hordeum
Inbreeding
Pollen
Seeds

A prospective observational study of the utility of early diagnostic laparoscopy for right lower abdominal pain: a safe and effective diagnostic and therapeutic tool

Guthrie, G. J. K., Johnston, T., Ewing, A., Mullen, R., Suttie, S. A. & Patil, P. V., 10 Jan 2019, In : Scottish Medical Journal. 7 p.

Research output: Contribution to journalArticle

Laparoscopy
Abdominal Pain
Observational Studies
Prospective Studies
Appendicitis
4 Downloads (Pure)

Area under the curve analysis of blood pressure reveals increased spontaneous locomotor activity in SPAK knock-in mice: relevance for hypotension induced by SPAK inhibition?

Burgess, K., Jovanović, S., Sudhir, R. & Jovanović, A., 3 Feb 2019, In : Physiological Reports. 7, 3, p. 1-12 12 p., e13997.

Research output: Contribution to journalArticle

Open Access
File
Controlled Hypotension
Locomotion
Area Under Curve
Blood Pressure
PAS domain kinases
1 Downloads (Pure)

A review of online platforms in training and surgical education

El Boghdady, M., Ewalds-Kvist, B. M. & Alijani, A., 28 Jan 2019, In : European Surgery - Acta Chirurgica Austriaca.

Research output: Contribution to journalReview article

Open Access
File
Education
Learning
Teaching
Technology
Professional Education
2 Downloads (Pure)
Open Access
File
presidential election
argumentation
social media
television
discourse analysis
4 Downloads (Pure)

Argumentation Theory for Mathematical Argument

Corneli, J., Martin, U., Murray-Rust, D., Rino Nesin, G. & Pease, A., 4 Jan 2019, In : Argumentation. 42 p.

Research output: Contribution to journalArticle

Open Access
File
argumentation
discourse
dialogue
Argumentation Theory
Discourse

A Sense of Place in Time

Valentine, L., 30 Jan 2019, In : Design Journal. 21, 4, p. 445-446 2 p., https://doi.org/10.1080/14606925.2018.1469875.

Research output: Contribution to journalEditorial

Sense of Place
Humility
Surprise
Participation
Courage

Association of Genetic Variants in NUDT15 with Thiopurine-Induced Myelosuppression in Patients with Inflammatory Bowel Disease

Walker, G. J., Harrison, J. W., Heap, G. A., Voskuil, M. D., Andersen, V., Anderson, C. A., Ananthakrishnan, A. N., Barrett, J. C., Beaugerie, L., Bewshea, C. M., Cole, A. T., Cummings, F. R., Daly, M. J., Ellul, P., Fedorak, R. N., Festen, E. A. M., Florin, T. H., Gaya, D. R., Halfvarson, J., Hart, A. L. & 30 othersHeerasing, N. M., Hendy, P., Irving, P. M., Jones, S. E., Koskela, J., Lindsay, J. O., Mansfield, J. C., McGovern, D., Parkes, M., Pollok, R. C. G., Ramakrishnan, S., Rampton, D. S., Rivas, M. A., Russell, R. K., Schultz, M., Sebastian, S., Seksik, P., Singh, A., So, K., Sokol, H., Subramaniam, K., Todd, A., Annese, V., Weersma, R. K., Xavier, R., Ward, R., Weedon, M. N., Goodhand, J. R., Kennedy, N. A. & Ahmad, T., 26 Feb 2019, In : JAMA - Journal of the American Medical Association. 321, 8, p. 753-761 9 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Genome-Wide Association Study
Exome
Odds Ratio
Chromosomes, Human, Pair 13
2 Downloads (Pure)

Association of ten gastrointestinal and other medical conditions with positivity to faecal occult blood testing in routine screening: a large prospective study of women in England

He, E., Alison, R., Blanks, R., Pirie, K., Reeves, G., Ward, R. L., Steele, R., Patnick, J., Canfell, K., Beral, V. & Green, J., 21 Jan 2019, In : International Journal of Epidemiology. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Occult Blood
England
Prospective Studies
Colorectal Neoplasms
Inflammatory Bowel Diseases

A study on effects of leaf and root characteristics on plant root water uptake

Ng, C. W. W., Wang, Z. J., Leung, A. K. & Ni, J. J., 1 Feb 2019, In : Geotechnique. 69, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

water uptake
suction
Water
Transpiration
Soils
1 Citation (Scopus)
8 Downloads (Pure)

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Grubb, A. L., McDonald, T. J., Rutters, F., Donnelly, L., Hattersley, A. T., Oram, R. A., Palmer, C., van der Heijden, A. A., Carr, F., Elders, P. J. M., Weedon, M., Slieker, R. C., 't Hart, L. M., Pearson, E., Shields, B. M. & Jones, A. G., Feb 2019, In : Diabetes Care. 42, 2, p. 208-214 7 p.

Research output: Contribution to journalArticle

Open Access
File
Type 1 Diabetes Mellitus
Autoantibodies
Type 2 Diabetes Mellitus
Insulin
Therapeutics

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., Van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M., Ahn, S-M. & 68 othersBoyault, S., Brock, J. E., Broeks, A., Butler, A., Desmedt, C., Dirix, L., Dronov, S., Fatima, A., Foekens, J. A., Gerstung, M., Hooijer, G. K. J., Jang, S. J., Jones, D. R., Kim, H-Y., King, T. A., Krishnamurthy, S., Lee, H. J., Lee, J-Y., Li, Y., McLaren, S., Menzies, A., Mustonen, V., O'Meara, S., Pauporté, I., Pivot, X., Purdie, C. A., Raine, K., Ramakrishnan, K., Rodríguez-González, F. G., Romieu, G., Sieuwerts, A. M., Simpson, P. T., Shepherd, R., Stebbings, L., Stefansson, O. A., Teague, J., Tommasi, S., Treilleux, I., Van den Eynden, G. G., Vermeulen, P., Vincent-Salomon, A., Yates, L., Caldas, C., Van't Veer, L., Tutt, A., Knappskog, S., Tan, B. K. T., Jonkers, J., Borg, Å., Ueno, N. T., Sotiriou, C., Viari, A., Futreal, P. A., Campbell, P. J., Span, P. N., Van Laere, S., Lakhani, S. R., Eyfjord, J. E., Thompson, A. M., Birney, E., Stunnenberg, H. G., van de Vijver, M. J., Martens, J. W. M., Børresen-Dale, A-L., Richardson, A. L., Kong, G., Thomas, G. & Stratton, M. R., 2019, In : Nature. 566, p. E1 1 p.

Research output: Contribution to journalArticle

Genome
Breast Neoplasms
Mutation

Automatic Brain Labeling via Multi-Atlas Guided Fully Convolutional Networks

Fang, L., Zhang, L., Nie, D., Cao, X., Rekik, I., Lee, S-W., He, H. & Shen, D., Jan 2019, In : Medical Image Analysis. 51, p. 157-168 12 p.

Research output: Contribution to journalArticle

Atlases
Labeling
Brain
Neuroimaging
Learning
4 Downloads (Pure)

A validation of the diathesis-stress model for depression in Generation Scotland

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Arnau-Soler, A., Adams, M. J., Clarke, T-K., MacIntyre, D. J., Milburn, K., Navrady, L., Hayward, C., McIntosh, A. & Thomson, P. A., 18 Jan 2019, In : Translational Psychiatry. 9, 1, p. 1-10 10 p., 25.

Research output: Contribution to journalArticle

Open Access
File
Disease Susceptibility
Scotland
Depression
Gene-Environment Interaction
Major Depressive Disorder

AVR2 targets BSL family members, which act as susceptibility factors to suppress host immunity

Turnbull, D., Wang, H., Breen, S., Malec, M., Naqvi, S., Yang, L., Welsh, L., Hemsley, P. A., Zhendong, T., Brunner, F., Gilroy, E. M. & Birch, P. R. J., 19 Feb 2019, In : Plant Physiology. 37 p.

Research output: Contribution to journalArticle

Phytophthora infestans
Immunity
Solanum tuberosum
immunity
Brassinosteroids
2 Downloads (Pure)

A well supported multi gene phylogeny of 52 dictyostelia

Schilde, C., Lawal, H. M., Kin, K., Shibano-Hayakawa, I., Inouye, K. & Schaap, P., May 2019, In : Molecular Phylogenetics and Evolution. 134, p. 66-73 8 p.

Research output: Contribution to journalArticle

Open Access
File
Phylogeny
phylogeny
gene
Genes
genome
1 Citation (Scopus)
antibiotic resistance
Wetlands
Climate Change
Antibiotics
Microbial Drug Resistance
Paternal Exposure
Cannabinoids
Epigenomics
Fathers
Episodic Memory

Bio-adrenomedullin as a marker of congestion in patients with new-onset and worsening heart failure

ter Maaten, J. M., Kremer, D., Demissei, B., Struck, J., Bergmann, A., Anker, S. D., Ng, L. L., Dickstein, K., Metra, M., Samani, N. J., Romaine, S. P. R., Cleland, J. G. F., Girerd, N., Lang, C., van Veldhuisen, D. J. & Voors, A. A., 6 Mar 2019, In : European Journal of Heart Failure. 12 p.

Research output: Contribution to journalArticle

Open Access
File
Adrenomedullin
Heart Failure
Edema
Hepatomegaly
Biomarkers
1 Downloads (Pure)

Body image transformation after breast cancer diagnosis and treatment in southern Thai women

Peerawong, T., Phenwan, T., Mahattanobon, S., Tulathamkij, K. & Pattanasattayavong, U., 2019, In : Sage Open Medicine. 7, p. 1-6 6 p., 529.

Research output: Contribution to journalArticle

Open Access
File
Body Image
Breast Neoplasms
Therapeutics
Focus Groups
Social Support
2 Citations (Scopus)

British Thoracic Society Guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 othersWhitters, D., Wilson, R. & Loebinger, M. R., Jan 2019, In : Thorax. 74, Suppl 1, p. 1-69 69 p.

Research output: Contribution to journalArticle

Open Access
File
3 Downloads (Pure)

Building bridges between experts and the public: a comparison of two-way communication formats for flooding and air pollution risk

Loroño-leturiondo, M., O'Hare, P., Cook, S., Hoon, S. R. & Illingworth, S., 24 Jan 2019, In : Geoscience Communication. 2, 1, p. 39-53 15 p.

Research output: Contribution to journalArticle

Open Access
File
atmospheric pollution
flooding
communication
comparison
pollution risk

CAPAM: the mRNA cap adenosine N6 methyltransferase

Cowling, V., 21 Jan 2019, In : Trends in Biochemical Sciences. 3 p., 1545.

Research output: Contribution to journalArticle

Open Access
mRNA guanylyltransferase
Methyltransferases
Adenosine
Messenger RNA
Methylation
5 Citations (Scopus)

Carbohydrate quality and human health: a series of systematic reviews and meta-analyses

Reynolds, A., Mann, J., Cummings, J., Winter, N., Mete, E. & Te Morenga, L., 2 Feb 2019, In : Lancet. 393, 10170, p. 434-445 12 p.

Research output: Contribution to journalArticle

Dietary Fiber
Meta-Analysis
Carbohydrates
Health
Risk Reduction Behavior