A systematic review of clinical trial registration in major respiratory journals 2010-2018

Nelli Sm Suntila, Alexandria Smith, Yusuf Al-Dabbagh, James D. Chalmers (Lead / Corresponding author)

Research output: Contribution to journalLetter

Abstract

Randomised clinical trials are regarded as the highest level of evidence for informing clinical guidelines and clinical practice. The robustness of conduct and reporting of the results of randomised clinical trials is therefore of primary importance. To improve the transparency and quality of reporting of clinical trials, the International Committee of Medical Journal Editors (ICMJE) endorsed a policy on mandatory registration of clinical trials, which came into effect in July 20053. The trial registration recommendations outlined by the ICMJE state that a trial must be registered in a publicly accessible registry, before the enrolment of the first study participants, in order to be considered for publication. This policy is designed to reduce publication bias, prevent selective reporting of desirable or non-reporting of undesirable results, and reduce research waste by making the research community aware of what questions are already being addressed by active trials.
Original languageEnglish
Article number1801491
JournalEuropean Respiratory Journal
Volume52
Issue number6
Early online date27 Sep 2018
DOIs
Publication statusPublished - 6 Dec 2018

Fingerprint

Randomized Controlled Trials
Clinical Trials
Publication Bias
Practice Guidelines
Research
Registries
Publications

Cite this

@article{c27ae537f5a94c6b9a823fbd37a59a32,
title = "A systematic review of clinical trial registration in major respiratory journals 2010-2018",
abstract = "Randomised clinical trials are regarded as the highest level of evidence for informing clinical guidelines and clinical practice. The robustness of conduct and reporting of the results of randomised clinical trials is therefore of primary importance. To improve the transparency and quality of reporting of clinical trials, the International Committee of Medical Journal Editors (ICMJE) endorsed a policy on mandatory registration of clinical trials, which came into effect in July 20053. The trial registration recommendations outlined by the ICMJE state that a trial must be registered in a publicly accessible registry, before the enrolment of the first study participants, in order to be considered for publication. This policy is designed to reduce publication bias, prevent selective reporting of desirable or non-reporting of undesirable results, and reduce research waste by making the research community aware of what questions are already being addressed by active trials.",
author = "Suntila, {Nelli Sm} and Alexandria Smith and Yusuf Al-Dabbagh and Chalmers, {James D.}",
year = "2018",
month = "12",
day = "6",
doi = "10.1183/13993003.01491-2018",
language = "English",
volume = "52",
journal = "European Respiratory Journal",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "6",

}

A systematic review of clinical trial registration in major respiratory journals 2010-2018. / Suntila, Nelli Sm; Smith, Alexandria; Al-Dabbagh, Yusuf; Chalmers, James D. (Lead / Corresponding author).

In: European Respiratory Journal, Vol. 52, No. 6, 1801491, 06.12.2018.

Research output: Contribution to journalLetter

TY - JOUR

T1 - A systematic review of clinical trial registration in major respiratory journals 2010-2018

AU - Suntila, Nelli Sm

AU - Smith, Alexandria

AU - Al-Dabbagh, Yusuf

AU - Chalmers, James D.

PY - 2018/12/6

Y1 - 2018/12/6

N2 - Randomised clinical trials are regarded as the highest level of evidence for informing clinical guidelines and clinical practice. The robustness of conduct and reporting of the results of randomised clinical trials is therefore of primary importance. To improve the transparency and quality of reporting of clinical trials, the International Committee of Medical Journal Editors (ICMJE) endorsed a policy on mandatory registration of clinical trials, which came into effect in July 20053. The trial registration recommendations outlined by the ICMJE state that a trial must be registered in a publicly accessible registry, before the enrolment of the first study participants, in order to be considered for publication. This policy is designed to reduce publication bias, prevent selective reporting of desirable or non-reporting of undesirable results, and reduce research waste by making the research community aware of what questions are already being addressed by active trials.

AB - Randomised clinical trials are regarded as the highest level of evidence for informing clinical guidelines and clinical practice. The robustness of conduct and reporting of the results of randomised clinical trials is therefore of primary importance. To improve the transparency and quality of reporting of clinical trials, the International Committee of Medical Journal Editors (ICMJE) endorsed a policy on mandatory registration of clinical trials, which came into effect in July 20053. The trial registration recommendations outlined by the ICMJE state that a trial must be registered in a publicly accessible registry, before the enrolment of the first study participants, in order to be considered for publication. This policy is designed to reduce publication bias, prevent selective reporting of desirable or non-reporting of undesirable results, and reduce research waste by making the research community aware of what questions are already being addressed by active trials.

UR - http://www.scopus.com/inward/record.url?scp=85058615321&partnerID=8YFLogxK

U2 - 10.1183/13993003.01491-2018

DO - 10.1183/13993003.01491-2018

M3 - Letter

VL - 52

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - 6

M1 - 1801491

ER -