Alzheimer's disease risk factor complement receptor 1 is associated with depression

Gillian Hamilton, Kathryn L. Evans, Donald J. MacIntyre, Ian J. Deary, Anna Dominiczak, Blair H. Smith, Andrew D. Morris, David J. Porteous, Pippa A. Thomson

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Abstract

    Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)6-9
    Number of pages4
    JournalNeuroscience Letters
    Volume510
    Issue number1
    DOIs
    Publication statusPublished - 2012

    Cite this

    Hamilton, G., Evans, K. L., MacIntyre, D. J., Deary, I. J., Dominiczak, A., Smith, B. H., ... Thomson, P. A. (2012). Alzheimer's disease risk factor complement receptor 1 is associated with depression. Neuroscience Letters, 510(1), 6-9. https://doi.org/10.1016/j.neulet.2011.12.059
    Hamilton, Gillian ; Evans, Kathryn L. ; MacIntyre, Donald J. ; Deary, Ian J. ; Dominiczak, Anna ; Smith, Blair H. ; Morris, Andrew D. ; Porteous, David J. ; Thomson, Pippa A. / Alzheimer's disease risk factor complement receptor 1 is associated with depression. In: Neuroscience Letters. 2012 ; Vol. 510, No. 1. pp. 6-9.
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    author = "Gillian Hamilton and Evans, {Kathryn L.} and MacIntyre, {Donald J.} and Deary, {Ian J.} and Anna Dominiczak and Smith, {Blair H.} and Morris, {Andrew D.} and Porteous, {David J.} and Thomson, {Pippa A.}",
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    Hamilton, G, Evans, KL, MacIntyre, DJ, Deary, IJ, Dominiczak, A, Smith, BH, Morris, AD, Porteous, DJ & Thomson, PA 2012, 'Alzheimer's disease risk factor complement receptor 1 is associated with depression', Neuroscience Letters, vol. 510, no. 1, pp. 6-9. https://doi.org/10.1016/j.neulet.2011.12.059

    Alzheimer's disease risk factor complement receptor 1 is associated with depression. / Hamilton, Gillian; Evans, Kathryn L.; MacIntyre, Donald J.; Deary, Ian J.; Dominiczak, Anna; Smith, Blair H.; Morris, Andrew D.; Porteous, David J.; Thomson, Pippa A.

    In: Neuroscience Letters, Vol. 510, No. 1, 2012, p. 6-9.

    Research output: Contribution to journalArticle

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    AU - Smith, Blair H.

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