CT staging of loco-regional breast cancer recurrence. A worthwhile practice?

S. Tennant, A. Evans, D. Macmillan, A. Lee, E. Cornford, J. James, I. Ellis

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    AIMS: To assess the usefulness of computed tomography of the chest, abdomen, and pelvis (CTCAP) in the detection of metastatic disease in patients presenting with loco-regional recurrence of breast cancer, and to identify subgroups particularly likely to have metastases. MATERIALS AND

    METHODS: Over a 32-month period, 63 patients with 65 recurrences underwent CTCAP, and were identified from the hospital's computerized radiology system.

    RESULTS: Twenty-one patients (32%) had metastases, including bony (n = 5, 8%), liver (n = 7, 11%), and thoracic disease (n = 11, 17%). Patients with recurrence in a conserved breast had lower rates of metastasis on CT than those with other sites of recurrence [three of 21 (14%) versus 18 of 44 (41%), p = 0.03]. Patients younger than 50 years at primary diagnosis or younger than 60 years at recurrence had statistically significantly higher rates of metastasis than older patients [10 of 16 (63%) versus 11 of 48 (23%), p = 0.003, and 13 of 23 (57%) versus eight of 42 (19%), p = 0.002, respectively].

    CONCLUSION: CT staging of patients presenting with loco-regional recurrence of breast cancer is a worthwhile practice. Younger patients and those with recurrence other than in the conserved breast are particularly likely to have metastatic disease. (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)885-890
    Number of pages6
    JournalClinical Radiology
    Volume64
    Issue number9
    DOIs
    Publication statusPublished - 2009

    Keywords

    • 20-YEAR FOLLOW-UP
    • RANDOMIZED-TRIAL
    • CONSERVING THERAPY
    • LOCOREGIONAL RECURRENCE
    • TOTAL MASTECTOMY
    • RISK-FACTORS
    • SURVIVAL
    • TOMOGRAPHY
    • METASTASES
    • CARCINOMA

    Cite this

    Tennant, S., Evans, A., Macmillan, D., Lee, A., Cornford, E., James, J., & Ellis, I. (2009). CT staging of loco-regional breast cancer recurrence. A worthwhile practice? Clinical Radiology, 64(9), 885-890. https://doi.org/10.1016/j.crad.2009.05.006
    Tennant, S. ; Evans, A. ; Macmillan, D. ; Lee, A. ; Cornford, E. ; James, J. ; Ellis, I. / CT staging of loco-regional breast cancer recurrence. A worthwhile practice?. In: Clinical Radiology. 2009 ; Vol. 64, No. 9. pp. 885-890.
    @article{680949e6d3cb4d25b06f41e4d4868f13,
    title = "CT staging of loco-regional breast cancer recurrence.: A worthwhile practice?",
    abstract = "AIMS: To assess the usefulness of computed tomography of the chest, abdomen, and pelvis (CTCAP) in the detection of metastatic disease in patients presenting with loco-regional recurrence of breast cancer, and to identify subgroups particularly likely to have metastases. MATERIALS ANDMETHODS: Over a 32-month period, 63 patients with 65 recurrences underwent CTCAP, and were identified from the hospital's computerized radiology system.RESULTS: Twenty-one patients (32{\%}) had metastases, including bony (n = 5, 8{\%}), liver (n = 7, 11{\%}), and thoracic disease (n = 11, 17{\%}). Patients with recurrence in a conserved breast had lower rates of metastasis on CT than those with other sites of recurrence [three of 21 (14{\%}) versus 18 of 44 (41{\%}), p = 0.03]. Patients younger than 50 years at primary diagnosis or younger than 60 years at recurrence had statistically significantly higher rates of metastasis than older patients [10 of 16 (63{\%}) versus 11 of 48 (23{\%}), p = 0.003, and 13 of 23 (57{\%}) versus eight of 42 (19{\%}), p = 0.002, respectively].CONCLUSION: CT staging of patients presenting with loco-regional recurrence of breast cancer is a worthwhile practice. Younger patients and those with recurrence other than in the conserved breast are particularly likely to have metastatic disease. (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.",
    keywords = "20-YEAR FOLLOW-UP, RANDOMIZED-TRIAL, CONSERVING THERAPY, LOCOREGIONAL RECURRENCE, TOTAL MASTECTOMY, RISK-FACTORS, SURVIVAL, TOMOGRAPHY, METASTASES, CARCINOMA",
    author = "S. Tennant and A. Evans and D. Macmillan and A. Lee and E. Cornford and J. James and I. Ellis",
    year = "2009",
    doi = "10.1016/j.crad.2009.05.006",
    language = "English",
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    Tennant, S, Evans, A, Macmillan, D, Lee, A, Cornford, E, James, J & Ellis, I 2009, 'CT staging of loco-regional breast cancer recurrence. A worthwhile practice?', Clinical Radiology, vol. 64, no. 9, pp. 885-890. https://doi.org/10.1016/j.crad.2009.05.006

    CT staging of loco-regional breast cancer recurrence. A worthwhile practice? / Tennant, S.; Evans, A.; Macmillan, D.; Lee, A.; Cornford, E.; James, J.; Ellis, I.

    In: Clinical Radiology, Vol. 64, No. 9, 2009, p. 885-890.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - CT staging of loco-regional breast cancer recurrence.

    T2 - A worthwhile practice?

    AU - Tennant, S.

    AU - Evans, A.

    AU - Macmillan, D.

    AU - Lee, A.

    AU - Cornford, E.

    AU - James, J.

    AU - Ellis, I.

    PY - 2009

    Y1 - 2009

    N2 - AIMS: To assess the usefulness of computed tomography of the chest, abdomen, and pelvis (CTCAP) in the detection of metastatic disease in patients presenting with loco-regional recurrence of breast cancer, and to identify subgroups particularly likely to have metastases. MATERIALS ANDMETHODS: Over a 32-month period, 63 patients with 65 recurrences underwent CTCAP, and were identified from the hospital's computerized radiology system.RESULTS: Twenty-one patients (32%) had metastases, including bony (n = 5, 8%), liver (n = 7, 11%), and thoracic disease (n = 11, 17%). Patients with recurrence in a conserved breast had lower rates of metastasis on CT than those with other sites of recurrence [three of 21 (14%) versus 18 of 44 (41%), p = 0.03]. Patients younger than 50 years at primary diagnosis or younger than 60 years at recurrence had statistically significantly higher rates of metastasis than older patients [10 of 16 (63%) versus 11 of 48 (23%), p = 0.003, and 13 of 23 (57%) versus eight of 42 (19%), p = 0.002, respectively].CONCLUSION: CT staging of patients presenting with loco-regional recurrence of breast cancer is a worthwhile practice. Younger patients and those with recurrence other than in the conserved breast are particularly likely to have metastatic disease. (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

    AB - AIMS: To assess the usefulness of computed tomography of the chest, abdomen, and pelvis (CTCAP) in the detection of metastatic disease in patients presenting with loco-regional recurrence of breast cancer, and to identify subgroups particularly likely to have metastases. MATERIALS ANDMETHODS: Over a 32-month period, 63 patients with 65 recurrences underwent CTCAP, and were identified from the hospital's computerized radiology system.RESULTS: Twenty-one patients (32%) had metastases, including bony (n = 5, 8%), liver (n = 7, 11%), and thoracic disease (n = 11, 17%). Patients with recurrence in a conserved breast had lower rates of metastasis on CT than those with other sites of recurrence [three of 21 (14%) versus 18 of 44 (41%), p = 0.03]. Patients younger than 50 years at primary diagnosis or younger than 60 years at recurrence had statistically significantly higher rates of metastasis than older patients [10 of 16 (63%) versus 11 of 48 (23%), p = 0.003, and 13 of 23 (57%) versus eight of 42 (19%), p = 0.002, respectively].CONCLUSION: CT staging of patients presenting with loco-regional recurrence of breast cancer is a worthwhile practice. Younger patients and those with recurrence other than in the conserved breast are particularly likely to have metastatic disease. (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

    KW - 20-YEAR FOLLOW-UP

    KW - RANDOMIZED-TRIAL

    KW - CONSERVING THERAPY

    KW - LOCOREGIONAL RECURRENCE

    KW - TOTAL MASTECTOMY

    KW - RISK-FACTORS

    KW - SURVIVAL

    KW - TOMOGRAPHY

    KW - METASTASES

    KW - CARCINOMA

    U2 - 10.1016/j.crad.2009.05.006

    DO - 10.1016/j.crad.2009.05.006

    M3 - Article

    C2 - 19664478

    VL - 64

    SP - 885

    EP - 890

    JO - Clinical Radiology

    JF - Clinical Radiology

    SN - 0009-9260

    IS - 9

    ER -