Diagnostic tools in male infertility

C L Barratt (Lead / Corresponding author), Justin C. St John

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

This review critically analyses the diagnostic value of conventional semen analysis and sperm function testing. It is clear from the data available that a high quality comprehensive semen assessment is a basic requirement in the diagnosis of the infertile couple. Sperm function testing has given disappointing results and a new generation of sperm function tests is required, which are cost effective, reliable and provide clinically significant information. In the future there will be an increasing use of molecular techniques to diagnose male infertility. Specific attention is given to the role of polymerase chain reaction in the diagnosis of genital infection and Y chromosomal and mitochondrial DNA deletions as examples.

Original languageEnglish
Pages (from-to)51-61
Number of pages11
JournalHuman Reproduction
Volume13 Suppl 1
DOIs
Publication statusPublished - Apr 1998

Fingerprint

Male Infertility
Spermatozoa
Semen Analysis
Mitochondrial DNA
Costs and Cost Analysis
Polymerase Chain Reaction
Infection

Keywords

  • Biopsy
  • Humans
  • Infertility, Male/diagnosis
  • Male
  • Molecular Biology/methods
  • Semen/physiology
  • Spermatozoa/physiology
  • Testis/pathology

Cite this

Barratt, C L ; St John, Justin C. / Diagnostic tools in male infertility. In: Human Reproduction. 1998 ; Vol. 13 Suppl 1. pp. 51-61.
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Diagnostic tools in male infertility. / Barratt, C L (Lead / Corresponding author); St John, Justin C.

In: Human Reproduction, Vol. 13 Suppl 1, 04.1998, p. 51-61.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Diagnostic tools in male infertility

AU - Barratt, C L

AU - St John, Justin C.

PY - 1998/4

Y1 - 1998/4

N2 - This review critically analyses the diagnostic value of conventional semen analysis and sperm function testing. It is clear from the data available that a high quality comprehensive semen assessment is a basic requirement in the diagnosis of the infertile couple. Sperm function testing has given disappointing results and a new generation of sperm function tests is required, which are cost effective, reliable and provide clinically significant information. In the future there will be an increasing use of molecular techniques to diagnose male infertility. Specific attention is given to the role of polymerase chain reaction in the diagnosis of genital infection and Y chromosomal and mitochondrial DNA deletions as examples.

AB - This review critically analyses the diagnostic value of conventional semen analysis and sperm function testing. It is clear from the data available that a high quality comprehensive semen assessment is a basic requirement in the diagnosis of the infertile couple. Sperm function testing has given disappointing results and a new generation of sperm function tests is required, which are cost effective, reliable and provide clinically significant information. In the future there will be an increasing use of molecular techniques to diagnose male infertility. Specific attention is given to the role of polymerase chain reaction in the diagnosis of genital infection and Y chromosomal and mitochondrial DNA deletions as examples.

KW - Biopsy

KW - Humans

KW - Infertility, Male/diagnosis

KW - Male

KW - Molecular Biology/methods

KW - Semen/physiology

KW - Spermatozoa/physiology

KW - Testis/pathology

U2 - 10.1093/humrep/13.suppl_1.51

DO - 10.1093/humrep/13.suppl_1.51

M3 - Review article

VL - 13 Suppl 1

SP - 51

EP - 61

JO - Human Reproduction

JF - Human Reproduction

SN - 0268-1161

ER -