European Code against Cancer 4th Edition

Alcohol drinking and cancer

Chiara Scoccianti, Michele Cecchini, Annie S. Anderson, Franco Berrino, Marie-Christine Boutron-Ruault, Carolina Espina, Timothy J. Key, Michael Leitzmann, Teresa Norat, Hilary Powers, Martin Wiseman, Isabelle Romieu (Lead / Corresponding author)

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    Abstract

    Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%-13%) of all cancer cases in men and 3% (95% CI: 1%-5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: "If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention."

    Original languageEnglish
    Pages (from-to)181-188
    Number of pages8
    JournalCancer Epidemiology
    Volume45
    Early online date2 Nov 2016
    DOIs
    Publication statusPublished - Dec 2016

    Fingerprint

    Alcohol Drinking
    Alcohols
    Neoplasms
    International Agencies
    Alcoholic Beverages
    Acetaldehyde
    Mouth Neoplasms
    Larynx
    Pharynx
    Esophagus
    Mouth
    Breast
    Ethanol
    Mortality
    Liver
    Research

    Keywords

    • Alcohol drinking
    • Cancer
    • Ethanol
    • Acetaldehyde
    • Disease
    • Primary prevention
    • Europe

    Cite this

    Scoccianti, C., Cecchini, M., Anderson, A. S., Berrino, F., Boutron-Ruault, M-C., Espina, C., ... Romieu, I. (2016). European Code against Cancer 4th Edition: Alcohol drinking and cancer. Cancer Epidemiology, 45, 181-188. https://doi.org/10.1016/j.canep.2016.09.011
    Scoccianti, Chiara ; Cecchini, Michele ; Anderson, Annie S. ; Berrino, Franco ; Boutron-Ruault, Marie-Christine ; Espina, Carolina ; Key, Timothy J. ; Leitzmann, Michael ; Norat, Teresa ; Powers, Hilary ; Wiseman, Martin ; Romieu, Isabelle. / European Code against Cancer 4th Edition : Alcohol drinking and cancer. In: Cancer Epidemiology. 2016 ; Vol. 45. pp. 181-188.
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    abstract = "Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10{\%} (95{\%} CI: 7{\%}-13{\%}) of all cancer cases in men and 3{\%} (95{\%} CI: 1{\%}-5{\%}) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: {"}If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention.{"}",
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    author = "Chiara Scoccianti and Michele Cecchini and Anderson, {Annie S.} and Franco Berrino and Marie-Christine Boutron-Ruault and Carolina Espina and Key, {Timothy J.} and Michael Leitzmann and Teresa Norat and Hilary Powers and Martin Wiseman and Isabelle Romieu",
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    Scoccianti, C, Cecchini, M, Anderson, AS, Berrino, F, Boutron-Ruault, M-C, Espina, C, Key, TJ, Leitzmann, M, Norat, T, Powers, H, Wiseman, M & Romieu, I 2016, 'European Code against Cancer 4th Edition: Alcohol drinking and cancer', Cancer Epidemiology, vol. 45, pp. 181-188. https://doi.org/10.1016/j.canep.2016.09.011

    European Code against Cancer 4th Edition : Alcohol drinking and cancer. / Scoccianti, Chiara; Cecchini, Michele; Anderson, Annie S.; Berrino, Franco; Boutron-Ruault, Marie-Christine; Espina, Carolina; Key, Timothy J.; Leitzmann, Michael; Norat, Teresa; Powers, Hilary; Wiseman, Martin; Romieu, Isabelle (Lead / Corresponding author).

    In: Cancer Epidemiology, Vol. 45, 12.2016, p. 181-188.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - European Code against Cancer 4th Edition

    T2 - Alcohol drinking and cancer

    AU - Scoccianti, Chiara

    AU - Cecchini, Michele

    AU - Anderson, Annie S.

    AU - Berrino, Franco

    AU - Boutron-Ruault, Marie-Christine

    AU - Espina, Carolina

    AU - Key, Timothy J.

    AU - Leitzmann, Michael

    AU - Norat, Teresa

    AU - Powers, Hilary

    AU - Wiseman, Martin

    AU - Romieu, Isabelle

    N1 - The European Code Against Cancer project was co-funded by the European Union [grant agreements No. 2011 53 05; 2010 53 04 and 2007IARC01] and the International Agency for Research on Cancer.

    PY - 2016/12

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    N2 - Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%-13%) of all cancer cases in men and 3% (95% CI: 1%-5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: "If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention."

    AB - Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%-13%) of all cancer cases in men and 3% (95% CI: 1%-5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: "If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention."

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    KW - Acetaldehyde

    KW - Disease

    KW - Primary prevention

    KW - Europe

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    M3 - Article

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    SP - 181

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    JO - Cancer Epidemiology

    JF - Cancer Epidemiology

    SN - 1877-7821

    ER -

    Scoccianti C, Cecchini M, Anderson AS, Berrino F, Boutron-Ruault M-C, Espina C et al. European Code against Cancer 4th Edition: Alcohol drinking and cancer. Cancer Epidemiology. 2016 Dec;45:181-188. https://doi.org/10.1016/j.canep.2016.09.011