In vitro comparison of Nyvad's system and ICDAS-II with lesion activity assessment for evaluation of severity and activity of occlusal caries lesions in primary teeth

M. M. Braga, F. M. Mendes, S. Martignon, D. N. J. Ricketts, K. R. Ekstrand

    Research output: Contribution to journalArticle

    46 Citations (Scopus)

    Abstract

    This in vitro study of occlusal surfaces on primary molars aimed to: (1) evaluate the reproducibility of the Nyvad and ICDAS-II visual systems in detecting caries; (2) to test the accuracy of the systems in estimating lesion depth, and (3) to examine the association between the Nyvad system and the Lesion Activity Assessment system, an adjunct to ICDAS-II. Two samples of extracted primary molars (sample 1, n = 38; sample 2, n = 69) were evaluated independently by 2 examiners. In this in vitro study, evaluation of plaque in the Nyvad system was not possible. Histology (sample 2) was used to validate lesion depth. Area under ROC curves (A(z)), sensitivity, specificity and percent agreement of both systems were calculated at D1, D2 and D3 thresholds. Both systems showed kappa for intra- and inter-examiner agreement >0.86 and good correlation with histology: Spearman rho = 0.73 (Nyvad) and 0.78 (ICDAS-II). They presented similar performances except that ICDAS-II showed significantly higher sensitivity (Nyvad 0.89; ICDAS 0.92) and A(z) (Nyvad 0.85; ICDAS 0.90) for the D1 threshold. The correlation between the systems for lesion activity (Cramer's V) was 0.71. Therefore, both visual systems are reliable and can estimate caries lesion depth on primary teeth. Under in vitro conditions, there is no major difference between the Nyvad system and Lesion Activity Assessment in assessing caries activity. Copyright (C) 2009 S. Karger AG, Basel

    Original languageEnglish
    Pages (from-to)405-412
    Number of pages8
    JournalCaries Research
    Volume43
    Issue number5
    DOIs
    Publication statusPublished - 2009

    Keywords

    • Activity, caries
    • Detection, caries
    • ICDAS-II
    • Nyvad's system
    • Occlusal surfaces
    • Primary teeth
    • Visual examination
    • African-American children
    • Dental caries
    • Diagnostic system
    • Carious lesions
    • Human enamel
    • Validity

    Cite this

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    title = "In vitro comparison of Nyvad's system and ICDAS-II with lesion activity assessment for evaluation of severity and activity of occlusal caries lesions in primary teeth",
    abstract = "This in vitro study of occlusal surfaces on primary molars aimed to: (1) evaluate the reproducibility of the Nyvad and ICDAS-II visual systems in detecting caries; (2) to test the accuracy of the systems in estimating lesion depth, and (3) to examine the association between the Nyvad system and the Lesion Activity Assessment system, an adjunct to ICDAS-II. Two samples of extracted primary molars (sample 1, n = 38; sample 2, n = 69) were evaluated independently by 2 examiners. In this in vitro study, evaluation of plaque in the Nyvad system was not possible. Histology (sample 2) was used to validate lesion depth. Area under ROC curves (A(z)), sensitivity, specificity and percent agreement of both systems were calculated at D1, D2 and D3 thresholds. Both systems showed kappa for intra- and inter-examiner agreement >0.86 and good correlation with histology: Spearman rho = 0.73 (Nyvad) and 0.78 (ICDAS-II). They presented similar performances except that ICDAS-II showed significantly higher sensitivity (Nyvad 0.89; ICDAS 0.92) and A(z) (Nyvad 0.85; ICDAS 0.90) for the D1 threshold. The correlation between the systems for lesion activity (Cramer's V) was 0.71. Therefore, both visual systems are reliable and can estimate caries lesion depth on primary teeth. Under in vitro conditions, there is no major difference between the Nyvad system and Lesion Activity Assessment in assessing caries activity. Copyright (C) 2009 S. Karger AG, Basel",
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    year = "2009",
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    In vitro comparison of Nyvad's system and ICDAS-II with lesion activity assessment for evaluation of severity and activity of occlusal caries lesions in primary teeth. / Braga, M. M.; Mendes, F. M.; Martignon, S.; Ricketts, D. N. J.; Ekstrand, K. R.

    In: Caries Research, Vol. 43, No. 5, 2009, p. 405-412.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - In vitro comparison of Nyvad's system and ICDAS-II with lesion activity assessment for evaluation of severity and activity of occlusal caries lesions in primary teeth

    AU - Braga, M. M.

    AU - Mendes, F. M.

    AU - Martignon, S.

    AU - Ricketts, D. N. J.

    AU - Ekstrand, K. R.

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    N2 - This in vitro study of occlusal surfaces on primary molars aimed to: (1) evaluate the reproducibility of the Nyvad and ICDAS-II visual systems in detecting caries; (2) to test the accuracy of the systems in estimating lesion depth, and (3) to examine the association between the Nyvad system and the Lesion Activity Assessment system, an adjunct to ICDAS-II. Two samples of extracted primary molars (sample 1, n = 38; sample 2, n = 69) were evaluated independently by 2 examiners. In this in vitro study, evaluation of plaque in the Nyvad system was not possible. Histology (sample 2) was used to validate lesion depth. Area under ROC curves (A(z)), sensitivity, specificity and percent agreement of both systems were calculated at D1, D2 and D3 thresholds. Both systems showed kappa for intra- and inter-examiner agreement >0.86 and good correlation with histology: Spearman rho = 0.73 (Nyvad) and 0.78 (ICDAS-II). They presented similar performances except that ICDAS-II showed significantly higher sensitivity (Nyvad 0.89; ICDAS 0.92) and A(z) (Nyvad 0.85; ICDAS 0.90) for the D1 threshold. The correlation between the systems for lesion activity (Cramer's V) was 0.71. Therefore, both visual systems are reliable and can estimate caries lesion depth on primary teeth. Under in vitro conditions, there is no major difference between the Nyvad system and Lesion Activity Assessment in assessing caries activity. Copyright (C) 2009 S. Karger AG, Basel

    AB - This in vitro study of occlusal surfaces on primary molars aimed to: (1) evaluate the reproducibility of the Nyvad and ICDAS-II visual systems in detecting caries; (2) to test the accuracy of the systems in estimating lesion depth, and (3) to examine the association between the Nyvad system and the Lesion Activity Assessment system, an adjunct to ICDAS-II. Two samples of extracted primary molars (sample 1, n = 38; sample 2, n = 69) were evaluated independently by 2 examiners. In this in vitro study, evaluation of plaque in the Nyvad system was not possible. Histology (sample 2) was used to validate lesion depth. Area under ROC curves (A(z)), sensitivity, specificity and percent agreement of both systems were calculated at D1, D2 and D3 thresholds. Both systems showed kappa for intra- and inter-examiner agreement >0.86 and good correlation with histology: Spearman rho = 0.73 (Nyvad) and 0.78 (ICDAS-II). They presented similar performances except that ICDAS-II showed significantly higher sensitivity (Nyvad 0.89; ICDAS 0.92) and A(z) (Nyvad 0.85; ICDAS 0.90) for the D1 threshold. The correlation between the systems for lesion activity (Cramer's V) was 0.71. Therefore, both visual systems are reliable and can estimate caries lesion depth on primary teeth. Under in vitro conditions, there is no major difference between the Nyvad system and Lesion Activity Assessment in assessing caries activity. Copyright (C) 2009 S. Karger AG, Basel

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    KW - Detection, caries

    KW - ICDAS-II

    KW - Nyvad's system

    KW - Occlusal surfaces

    KW - Primary teeth

    KW - Visual examination

    KW - African-American children

    KW - Dental caries

    KW - Diagnostic system

    KW - Carious lesions

    KW - Human enamel

    KW - Validity

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    DO - 10.1159/000239755

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