Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia

R.P. Ryan, Yvonne McCarthy, Steven A. Watt, Karsten Niehaus, J. Maxwell Dow

    Research output: Contribution to journalArticle

    39 Citations (Scopus)

    Abstract

    Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic
    pathogen.

    Original languageEnglish
    Pages (from-to)5013-5019
    Number of pages7
    JournalJournal of Bacteriology
    Volume191
    Issue number15
    DOIs
    Publication statusPublished - 1 Aug 2009

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    Burkholderia cenocepacia
    Virulence
    Fatty Acids
    bone marrow soluble immune-response suppressor
    2-dodecenoic acid

    Cite this

    Ryan, R.P. ; McCarthy, Yvonne ; Watt, Steven A. ; Niehaus, Karsten ; Dow, J. Maxwell. / Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia. In: Journal of Bacteriology. 2009 ; Vol. 191, No. 15. pp. 5013-5019.
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    Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia. / Ryan, R.P.; McCarthy, Yvonne; Watt, Steven A.; Niehaus, Karsten; Dow, J. Maxwell.

    In: Journal of Bacteriology, Vol. 191, No. 15, 01.08.2009, p. 5013-5019.

    Research output: Contribution to journalArticle

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    AU - Niehaus, Karsten

    AU - Dow, J. Maxwell

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