LigaSure compared with ligatures and endoclips in experimental appendectomy

How safe is it?

L. Elemen, M. Tugay, A. Akay, Y. Yazir, S. Ceylan, S. Aydin, K. Yanar

    Research output: Contribution to journalArticle

    21 Citations (Scopus)

    Abstract

    Purpose The present study aims to compare strength, healing, and inflammation of appendiceal stumps closed by LigaSure Precise (Valleylab, Boulder, CO, USA) device, ligatures using polyglactin 910 (Vicryl, Ethicon, Edinburgh, UK) and endoclips (Ligaclip ERCA, Ethicon, OH, USA), and operation time (OT) in experimental appendectomy. Methods Forty-eight Sprague-Dawley rats were divided into two (Group A and B). Each group was further subdivided into three subgroups (AS, AC, AL, BS, BC, BL) containing eight rats. Appendectomy was performed and stump was closed by ligatures in S, by endoclips in C and by LigaSure in L subgroups. OT was recorded. In Group A, cecum bursting pressures (BP) were determined instantly after the operation. In Group B, BP, histological evaluations, and measurements of collagen contents estimated by the tissue hydroxyproline (HPL) level were made on the seventh postoperative day. Statistical analyses were performed with Kruskal-Wallis test and Mann-Whitney U test. P value was considered significant at less than 0.05. Results BPs of subgroups were comparable on postoperative immediate period and day 7. HPLs and OTs were significantly better in L subgroups. BL had the least inflammation. Conclusion Better healing, less inflammation, shorter OT, and equal strength achieved with LigaSure device comparing with polyglactin 910 ties and endoclips in experimental appendectomy is encouraging.
    Original languageEnglish
    Pages (from-to)539-545
    Number of pages7
    JournalPediatric Surgery International
    Volume26
    Issue number5
    DOIs
    Publication statusPublished - 2010

    Fingerprint

    Polyglactin 910
    Appendectomy
    Ligation
    Inflammation
    Pressure
    Equipment and Supplies
    Cecum
    Hydroxyproline
    Carbon Monoxide
    Nonparametric Statistics
    Postoperative Period
    Sprague Dawley Rats
    Collagen

    Cite this

    Elemen, L. ; Tugay, M. ; Akay, A. ; Yazir, Y. ; Ceylan, S. ; Aydin, S. ; Yanar, K. / LigaSure compared with ligatures and endoclips in experimental appendectomy : How safe is it?. In: Pediatric Surgery International. 2010 ; Vol. 26, No. 5. pp. 539-545.
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    title = "LigaSure compared with ligatures and endoclips in experimental appendectomy: How safe is it?",
    abstract = "Purpose The present study aims to compare strength, healing, and inflammation of appendiceal stumps closed by LigaSure Precise (Valleylab, Boulder, CO, USA) device, ligatures using polyglactin 910 (Vicryl, Ethicon, Edinburgh, UK) and endoclips (Ligaclip ERCA, Ethicon, OH, USA), and operation time (OT) in experimental appendectomy. Methods Forty-eight Sprague-Dawley rats were divided into two (Group A and B). Each group was further subdivided into three subgroups (AS, AC, AL, BS, BC, BL) containing eight rats. Appendectomy was performed and stump was closed by ligatures in S, by endoclips in C and by LigaSure in L subgroups. OT was recorded. In Group A, cecum bursting pressures (BP) were determined instantly after the operation. In Group B, BP, histological evaluations, and measurements of collagen contents estimated by the tissue hydroxyproline (HPL) level were made on the seventh postoperative day. Statistical analyses were performed with Kruskal-Wallis test and Mann-Whitney U test. P value was considered significant at less than 0.05. Results BPs of subgroups were comparable on postoperative immediate period and day 7. HPLs and OTs were significantly better in L subgroups. BL had the least inflammation. Conclusion Better healing, less inflammation, shorter OT, and equal strength achieved with LigaSure device comparing with polyglactin 910 ties and endoclips in experimental appendectomy is encouraging.",
    author = "L. Elemen and M. Tugay and A. Akay and Y. Yazir and S. Ceylan and S. Aydin and K. Yanar",
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    Elemen, L, Tugay, M, Akay, A, Yazir, Y, Ceylan, S, Aydin, S & Yanar, K 2010, 'LigaSure compared with ligatures and endoclips in experimental appendectomy: How safe is it?', Pediatric Surgery International, vol. 26, no. 5, pp. 539-545. https://doi.org/10.1007/s00383-010-2557-x

    LigaSure compared with ligatures and endoclips in experimental appendectomy : How safe is it? / Elemen, L.; Tugay, M.; Akay, A.; Yazir, Y.; Ceylan, S.; Aydin, S.; Yanar, K.

    In: Pediatric Surgery International, Vol. 26, No. 5, 2010, p. 539-545.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - LigaSure compared with ligatures and endoclips in experimental appendectomy

    T2 - How safe is it?

    AU - Elemen, L.

    AU - Tugay, M.

    AU - Akay, A.

    AU - Yazir, Y.

    AU - Ceylan, S.

    AU - Aydin, S.

    AU - Yanar, K.

    N1 - Copyright 2010 Elsevier B.V., All rights reserved.

    PY - 2010

    Y1 - 2010

    N2 - Purpose The present study aims to compare strength, healing, and inflammation of appendiceal stumps closed by LigaSure Precise (Valleylab, Boulder, CO, USA) device, ligatures using polyglactin 910 (Vicryl, Ethicon, Edinburgh, UK) and endoclips (Ligaclip ERCA, Ethicon, OH, USA), and operation time (OT) in experimental appendectomy. Methods Forty-eight Sprague-Dawley rats were divided into two (Group A and B). Each group was further subdivided into three subgroups (AS, AC, AL, BS, BC, BL) containing eight rats. Appendectomy was performed and stump was closed by ligatures in S, by endoclips in C and by LigaSure in L subgroups. OT was recorded. In Group A, cecum bursting pressures (BP) were determined instantly after the operation. In Group B, BP, histological evaluations, and measurements of collagen contents estimated by the tissue hydroxyproline (HPL) level were made on the seventh postoperative day. Statistical analyses were performed with Kruskal-Wallis test and Mann-Whitney U test. P value was considered significant at less than 0.05. Results BPs of subgroups were comparable on postoperative immediate period and day 7. HPLs and OTs were significantly better in L subgroups. BL had the least inflammation. Conclusion Better healing, less inflammation, shorter OT, and equal strength achieved with LigaSure device comparing with polyglactin 910 ties and endoclips in experimental appendectomy is encouraging.

    AB - Purpose The present study aims to compare strength, healing, and inflammation of appendiceal stumps closed by LigaSure Precise (Valleylab, Boulder, CO, USA) device, ligatures using polyglactin 910 (Vicryl, Ethicon, Edinburgh, UK) and endoclips (Ligaclip ERCA, Ethicon, OH, USA), and operation time (OT) in experimental appendectomy. Methods Forty-eight Sprague-Dawley rats were divided into two (Group A and B). Each group was further subdivided into three subgroups (AS, AC, AL, BS, BC, BL) containing eight rats. Appendectomy was performed and stump was closed by ligatures in S, by endoclips in C and by LigaSure in L subgroups. OT was recorded. In Group A, cecum bursting pressures (BP) were determined instantly after the operation. In Group B, BP, histological evaluations, and measurements of collagen contents estimated by the tissue hydroxyproline (HPL) level were made on the seventh postoperative day. Statistical analyses were performed with Kruskal-Wallis test and Mann-Whitney U test. P value was considered significant at less than 0.05. Results BPs of subgroups were comparable on postoperative immediate period and day 7. HPLs and OTs were significantly better in L subgroups. BL had the least inflammation. Conclusion Better healing, less inflammation, shorter OT, and equal strength achieved with LigaSure device comparing with polyglactin 910 ties and endoclips in experimental appendectomy is encouraging.

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    U2 - 10.1007/s00383-010-2557-x

    DO - 10.1007/s00383-010-2557-x

    M3 - Article

    VL - 26

    SP - 539

    EP - 545

    JO - Pediatric Surgery International

    JF - Pediatric Surgery International

    SN - 0179-0358

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